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Chapter 9: Biotechnology Principles and Processes — Online MCQ Test

BIOLOGY · CLASS 12 INTER II YEAR · Andhra State Board
Practice Chapter 9: Biotechnology Principles and Processes with a free chapter-wise online MCQ test. This chapter covers: Biotechnology Recombinant DNA Restriction Enzymes DNA Ligase Cloning Vector Gene Cloning PCR Bioreactor Genetic Engineering Transformation. AI-generated questions from basic to board-exam level, with instant results and explanations.

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Chapter 9: Biotechnology Principles and Processes — Important Questions & Answers

Which enzyme is used to join two DNA fragments by forming phosphodiester bonds?
  • A. DNA polymerase
  • B. DNA ligase
  • C. Restriction endonuclease
  • D. RNA polymerase
Answer: B. DNA ligase
DNA ligase joins DNA fragments by sealing nicks and forming phosphodiester bonds between adjacent nucleotides.
Restriction enzymes are also known as:
  • A. Molecular scissors
  • B. Molecular glue
  • C. Cloning vehicles
  • D. Thermal cyclers
Answer: A. Molecular scissors
Restriction enzymes cut DNA at specific recognition sequences, so they are commonly called molecular scissors.
Which of the following is NOT an essential feature of a cloning vector according to NCERT?
  • A. Origin of replication
  • B. Selectable marker
  • C. Cloning site
  • D. Centromere for mitosis in bacteria
Answer: D. Centromere for mitosis in bacteria
Bacterial cloning vectors require ori, selectable marker and cloning sites; bacteria do not use centromeres for mitosis.
EcoRI recognizes the sequence 5'-GAATTC-3'. After cutting, it produces sticky ends because:
  • A. It cuts both strands exactly at the centre, producing blunt ends
  • B. It cuts the two DNA strands at different positions, producing overhangs
  • C. It removes all adenine bases from DNA
  • D. It converts double-stranded DNA into RNA
Answer: B. It cuts the two DNA strands at different positions, producing overhangs
EcoRI cuts asymmetrically between G and A on opposite strands, producing single-stranded overhangs called sticky ends.
In the naming of EcoRI, what does the letter R represent?
  • A. The strain of Escherichia coli
  • B. The genus of the source organism
  • C. The species of the source organism
  • D. The order in which the enzyme was isolated
Answer: A. The strain of Escherichia coli
In EcoRI, E represents Escherichia, co represents coli, R represents the strain, and I indicates it was the first enzyme isolated from that strain.