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Chapter 12: Tools and Techniques — Online MCQ Test

BIOTECHNOLOGY · Grade 11 · CBSE(NCERT)
Practice Chapter 12: Tools and Techniques with a free chapter-wise online MCQ test. This chapter covers: Microscopy chromatography centrifugation electrophoresis PCR polymerase chain reaction laboratory techniques biotechnology tools DNA analysis molecular diagnostics. AI-generated questions from basic to board-exam level, with instant results and explanations.

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Chapter 12: Tools and Techniques — Important Questions & Answers

Which instrument is commonly used to observe very small biological samples by passing light through them?
  • A. Microscope
  • B. Centrifuge
  • C. Chromatograph
  • D. Spectrophotometer
Answer: A. Microscope
A microscope is used to magnify and view tiny objects such as cells and tissues. It is a fundamental tool in biotechnology laboratories.
In PCR, the enzyme that synthesizes new DNA strands is called:
  • A. DNA ligase
  • B. Taq polymerase
  • C. Restriction endonuclease
  • D. RNA polymerase
Answer: B. Taq polymerase
Taq polymerase is a heat-stable DNA polymerase used in PCR to extend primers and synthesize DNA. It is isolated from Thermus aquaticus.
Why is centrifugation used in biotechnology laboratories?
  • A. To increase the size of cells
  • B. To separate components based on density
  • C. To amplify DNA
  • D. To stain chromosomes
Answer: B. To separate components based on density
Centrifugation separates particles according to their density by spinning the sample at high speed. Heavier particles move outward and settle faster.
A DNA sample contains fragments of different lengths. After electrophoresis, which fragment is expected to move the farthest from the well?
  • A. The largest fragment
  • B. The fragment with the highest mass only
  • C. The smallest fragment
  • D. All fragments move equally far
Answer: C. The smallest fragment
Smaller DNA fragments face less resistance in the gel and migrate faster. Therefore, they move farther than larger fragments.
A band on an electrophoresis gel remains very close to the well. Which is the most likely reason?
  • A. The fragment is very small
  • B. The fragment is very large
  • C. The DNA has no charge
  • D. The gel contains no pores
Answer: B. The fragment is very large
Large DNA fragments move slowly through the gel and therefore stay closer to the well. Smaller fragments travel farther under the same conditions.